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Athero- and AAA-Express
Athero- and Aneurysm-Express Biobank Studies...
Description
The Athero-Express Biobank Study (AE) and the Abdominal Aortic Aneurysm-Express Biobank Study (AAA) are two ongoing, prospective biobank studies initiated in 2002 and 2003, respectively. Together, they comprise detailed histological and clinical data...
General Design
- Type
- Biobank, Cohort study, Databank, Disease specific
- Cohort type
- Clinical cohort, Case only
- Data collection type
- Retrospective, Prospective
- Design
- Longitudinal
- Design description
- The Athero-Express Biobank Study (AE) is a longitudinal cross-sectional biobank study collecting blood and atherosclerotic plaque samples from patients undergoing endarterectomy. Clinical data is collected through standardised questionnaires and supplemented by querying electronic health records when needed. Patients are followed up to 3 years after surgery.
- Start/End data collection
- 2002 (ongoing)
- Design papers
- Aneurysm-express: human abdominal aortic aneurysm wall expression in relation to heterogeneity and vascular events - rationale and design
- Athero-express: differential atherosclerotic plaque expression of mRNA and protein in relation to cardiovascular events and patient characteristics. Rationale and design
- PID
- https://doi.org/10.71739/371b-mg77
Population
- Countries
- Netherlands (the)
- Number of participants
- 3500
- Population age groups
- Adult (18+ years)
- Main medical condition
- IX Diseases of the circulatory system
- I70-I79 Diseases of arteries, arterioles and capillaries
- I70 Atherosclerosis
- I70.0 Atherosclerosis of aorta
- I70.1 Atherosclerosis of renal artery
- I70.2 Atherosclerosis of arteries of extremities
- I70.8 Atherosclerosis of other arteries
- I71 Aortic aneurysm and dissection
- I71.0 Dissection of aorta [any part]
- I71.3 Abdominal aortic aneurysm, ruptured
- I71.4 Abdominal aortic aneurysm, without mention of rupture
- I71.8 Aortic aneurysm of unspecified site, ruptured
- I71.9 Aortic aneurysm of unspecified site, without mention of rupture
- I72 Other aneurysm and dissection
- I72.0 Aneurysm and dissection of carotid artery
- I72.1 Aneurysm and dissection of artery of upper extremity
- I72.2 Aneurysm and dissection of renal artery
- I72.3 Aneurysm and dissection of iliac artery
- I72.4 Aneurysm and dissection of artery of lower extremity
- I72.5 Aneurysm and dissection of other precerebral arteries
- I72.6 Aneurysm and dissection of vertebral artery
- I72.8 Aneurysm and dissection of other specified arteries
- I72.9 Aneurysm and dissection of unspecified site
- Inclusion criteria
- Health status inclusion criterion
- Hospital patient inclusion criterion
Organisations
Lead organisations
- University Medical Center Utrecht (UMC)Netherlands (the)https://www.umcutrecht.nl
Data originator, Data holder, Data provider, Data access provider
Contributors
- dr. SW (Sander) van der LaanUniversity Medical Center Utrechts.w.vanderlaan-2@umcutrecht.nl
Principal Investigator, Data manager
Available Data & Samples
Data categories
Survey data
Sample categories
- Blood
- Blood (whole)
- Plasma
- Serum
- Genetic material
- DNA
- RNA
- Tissue (FFPE)
- Cardiovascular System - Tissue (FFPE)
- Arteries - Tissue (FFPE)
- Tissue (Frozen)
- Cardiovascular System - Tissue (Frozen)
- Arteries - Tissue (Frozen)
Areas of information
- Socio-demographic and economic characteristics
- Age/birthdate
- Sex/gender
- Education
- Birthplace
- Ethnicity, race and religion
- Other socio-demographic and economic characteristics
- Lifestyle and behaviours
- Tobacco
- Alcohol
- Drugs
- Nutrition
- Physical activity
- Birth, pregnancy and reproductive health history
- Puberty, menstruation, menopause and andropause
- Contraception
- Pregnancy, delivery and birth
- Perception of health, quality of life, development and functional limitations
- Quality of life
- Symptoms and signs
- Symptoms and signs involving the circulatory and respiratory systems (R00-R09)
- Symptoms and signs involving cognition, perception, emotional state and behaviour (R40-R46)
- General symptoms and signs (R50-R69)
- Medication and supplements
- Medication and supplement intake
- Non-pharmacological interventions
- Surgical interventions
- Death
- Vital status
- Cause of death
- Other end of life or death-related information
- Physical measures and assessments
- Physical characteristics
- Anthropometry
- Circulation and respiration
- Laboratory measures
- Hematology
- Biochemistry
- Histology
- Genomics
- Cognition, personality and psychological measures and assessments
- Psychological distress and emotions
- Administrative information
- Identifiers
- Date and time-related information
- Questionnaire and interview-related information
- Physical and cognitive measure and biosample-related information
- Data and sample collection center-related information
- Other administrative information
Subpopulations
List of subpopulations for this resource...
| Name | Description | Number of participants | |
|---|---|---|---|
No results for current selection |
Collection events
List of collection events defined for this resource...
| Name | Description | Participants | Start end year | |
|---|---|---|---|---|
No results for current selection |
Networks
Part of networks...
Publications
Aneurysm-express: human abdominal aortic aneurysm wall expression in relation to heterogeneity and vascular events - rationale and design
Athero-express: differential atherosclerotic plaque expression of mRNA and protein in relation to cardiovascular events and patient characteristics. Rationale and design
Access conditions
- Data access conditions
- health or medical or biomedical research
- disease specific research
- Data use conditions
- research specific restrictions
- not for profit, non commercial use only
- collaboration required
- geographical restriction
- return to database or resource
- Data access fee
- false
- Release type
- Closed dataset
- Prelinked
- false
- Linkage options
- Possibility to link with data from RIVM and CBS.