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ALL10
Protocol ALL 10, protocol voor diagnostiek en behandeling van kinderen en adolescenten (1-19 jaar) met Acute Lymfatische Leukemie (ALL)...
Description
The aim of Protocol ALL-10 is to improve the overall treatment results in terms of EFS and to decrease treatment intensity in patients with a pEFS of >95%. Therapy will be tailored according to the risk of relapse as determined by the MRD levels at 2...
General Design
- Type
- Clinical trial
- Data collection type
- Prospective
- Design
- Longitudinal
- Design description
- The aim of Protocol ALL-10 is to improve the overall treatment results in terms of EFS and to decrease treatment intensity in patients with a pEFS of >95%. Therapy will be tailored according to the risk of relapse as determined by the MRD levels at 2 time points during the first months of therapy. This tailored therapy should lead to less intensive therapy for patients with low risk of relapse and to intensification of therapy for patients with medium and high risk of relapse.
- Start/End data collection
- 2004 until 2012
- Design paper
- Successful Therapy Reduction and Intensification for Childhood Acute Lymphoblastic Leukemia Based on Minimal Residual Disease Monitoring: Study ALL10 From the Dutch Childhood Oncology Group
- PID
- https://doi.org/10.71739/jr71-6h42
- External identifiers
- METc number: MEC-2004-203
Population
- Countries
- Netherlands (the)
- Number of participants
- 778
- Population age groups
- Infants and toddlers (2-23 months), Child (2-12 years), Adolescent (13-17 years), Young adult (18-24 years)
- Main medical condition
- II Neoplasms
- C00-C97 Malignant neoplasms
- C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
- C91.0 Acute lymphoblastic leukaemia [ALL]
- C91.6 Prolymphocytic leukaemia of T-cell type
- Inclusion criteria
- Age group inclusion criterion
- Health status inclusion criterion
- Other inclusion criteria
- Child (1-19 years)
Organisations
Lead organisations
- Princess Máxima CenterNetherlands (the)https://www.prinsesmaximacentrum.nl
Data holder, Researcher, Data access provider
Contributors
- Hester de Groot-Kruseman
Primary contact
Available Data & Samples
Data categories
- Biological samples
- Medical records
Sample categories
- Blood
- Blood (whole)
- Plasma
- Serum
- Cells
- Bone marrow cells
- Granulocytes
- Leukocytes, Mononuclear
Areas of information
- Symptoms and signs
- General symptoms and signs (R50-R69)
- Symptoms related to multiple categories
- Medication and supplements
- Chemotherapy interventions
- Death
- Vital status
- Cause of death
- Other end of life or death-related information
- Physical measures and assessments
- Physical characteristics
- Other physical measures and assessments
- Laboratory measures
- Hematology
- Biochemistry
- Microbiology
- Virology
- Histology
- Other laboratory measures
Subpopulations
List of subpopulations for this resource...
| Name | Description | Number of participants | |
|---|---|---|---|
No results for current selection |
Collection events
List of collection events defined for this resource...
| Name | Description | Participants | Start end year | |
|---|---|---|---|---|
No results for current selection |
Networks
Part of networks...
Publications
Access conditions
- Data access conditions
- health or medical or biomedical research
- disease specific research
- Data access fee
- false
- Release type
- Closed dataset
- Prelinked
- false